John Whitehead

Founder and Former Director

Professor Whitehead is Head of the Department of Mathematics and Statistics at Lancaster University. He has served as President of the International Society of Clinical Biostatistics and as Editor of Statistics in Medicine. Professor Whitehead’s research interests include sequential methods for clinical trials, Bayesian decision theory for phase I dose-finding studies and the design of phase II studies. He is particularly interested in methodology for dealing with survival and ordered categorical data. He is involved in numerous collaborative research projects with the pharmaceutical industry, and in the presentation of short professional development courses on statistical methodology for drug development.

John Whitehead
The MPS Research Unit
Department of Mathematics and Statistics
Fylde College; Lancaster University Lancaster, Lancashire LA1 4YF
+44 (0)1524 592350

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Research Interests

  • Group sequential designs
  • Dose-finding studies
  • Adaptive designs

Selected Publications

  • Whitehead, J., Branson, M., Todd, S., ( 2010 ). A combined score test for binary and ordinal endpoints from clinical trials . Statistics in Medicine 29, 521-532
  • Whitehead, J., Valdés-Márquez, E., Lissmats, A., ( 2009 ). A simple two-stage design for quantitative responses with application to a study in diabetic neuropathic pain . Pharmaceutical Statistics 8, 125-135
  • Whitehead, J., Valdés-Márquez, E., Johnson, P., Graham, G., ( 2008 ). Bayesian sample size for exploratory clinical trials incorporating historical data . Statistics in Medicine 27. 2307-2327
  • Kelly, P., Stallard, N., Zhou, Y., Whitehead, J., Bowman, C., ( 2006 ). Sequential genome-wide association studies for monitoring adverse events in the clinical evaluation of new drugs . Statistics in Medicine 25, 3081-3092
  • Whitehead, J., ( 1997 ). The Design and Analysis of Sequential Clinical Trials . Revised Second Edition, Chichester: Wiley.